MyBioSource.com's MED14 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Immunohistochemistry. The MED14 Antibody was generated using MED14 as the antigen and it reacts with Human.
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Yoshikawa H., Genomics 49:237-246(1998).Ryu S., Nature 397:446-450(1999).Rachez C., Nature 398:824-828(1999)